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At the indicated time (20 min and 60 min), an aliquot of 70 L was removed from each experimental reaction and pipetting into 175 L of acetonitrile at 0 C to quench the reaction ( t = 0 min was determined using the reaction without pancreatin)

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From there, your doctor may increase your dose by 2.5 mg increments every month, depending on your treatment goals and how your body responds

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