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SC is often selected when patients self-inject frequently, when comfort is a priority, or when body composition makes IM targeting difficult

Long-term effects are still being studied in Phase 3 trials

Synthetic 39-amino-acid peptide

A phase I/II clinical trial found that the most common side effects were mild and transient (Teichman et al., 2006): Injection site reactions (redness, mild swelling) Headaches Flushing or warmth Temporary water retention Joint tightness or tingling Transient fatigue or dizziness Serious adverse events are rare when the peptide is used under medical supervision at appropriate doses

& Abramov, A