Recent polls show that about 12% of American adults are currently taking a Until recently, these medications like Ozempic and Zepbound, were administered only by self-injection
Circadian rhythm disruption causes a decrease in GLP-1 production.[ref] Blue light exposure at night from screens (phone, TV, tablet) or LED lightbulbs causes circadian rhythm disruption
Our overarching framework is that gutbrain (and other periphery-to-brain) endocrine signaling may play a role in AUD (and potentially other substance use disorders) and could therefore represent novel targets for treatment development
The GLP-1 receptor agonist, liraglutide, fails to slow disease progression in SOD1 G93A and TDP-43 Q331K transgenic mouse models of ALS
The data showing this translates into measurably better PCOS fertility outcomes pregnancy rate, live birth rate, egg-retrieval quality scores in IVF is suggestive in some smaller trials and underwhelming in others