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Diabetes and obesity, both of which are associated with the secretion of pro-inflammatory adipokines and the reduced availability of nitric oxide, may lead to the occurrence of HFpEF in young individuals due to myocardial remodeling and fibrosis [7, 34]

Some of the GLP-1 agonists drugs in the pipeline include orforglipron by Eli Lilly and company , survodutide by Boehringer Ingelheim, danuglipron by Pfizer , and retatrutide by Eli Lilly and company , among others

10.1152/ajpendo.00308.2017 69 MathesC

Historically used to treat diabetes and obesity, GLP-1 medications have untapped potential in addressing broader womens health conditions

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