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In differentiated human adipocytes in vitro , GLP-1 can regulate the expression of adipogenesis and lipolytic genes [47]
all should be discontinued when pregnancy is recognized) [1] [4] After prolonged treatment interruptions (typically 2 consecutive missed doses or longer gaps), re-titration from the initial dose may be necessary according to product-specific guidelines to minimize gastrointestinal side effects
Receptor agonists bind to receptors and trigger intracellular signaling pathways that modulate physiological functions
Methods Enzymol 233:357363
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