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Manufacturers advise that you stop these medicines before you become pregnant, in some cases three months before a planned pregnancy
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This structural change dramatically reduces IGF-1s binding affinity for IGFBPs (insulin-like growth factor-binding proteins), thereby extending its active half-life from approximately 12 minutes to 2030 hours
Modern medicinal chemistry can extend peptide half-life, improve receptor selectivity, reduce degradation and change how a peptide is delivered
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