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Recommendation: Start b12 supplementation immediately, independent of semaglutide use
The NIH factsheet explains that no tolerable upper intake level has been set for B12, because it has a low potential for toxicity in healthy people
For comparison, semaglutide alone achieved approximately 14.9% in the STEP 1 trial, and tirzepatide achieved approximately 20.9% in SURMOUNT-1 at 72 weeks
But I bring this up on the heels of us talking about the calcium scans because it gets really confusing for people, Juliana, as you know, where, you know, for a while it was sort of the general consensus about avoiding eating a lot of red meat
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