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Systematic reviews and meta-analyses of randomized trials have further confirmed that while GLP-1RAs lower body weight and fat mass significantly, they do not appear to exert an independent detrimental effect on skeletal muscle index beyond expected proportional reductions [25]
In trials where semaglutide was added on to basal insulin with or without metformin, severe hypoglycemia (requiring the assistance of another person) was reported in 1.5% of semaglutide-treated patients
Whether any of these peptides is appropriate for you depends on your individual goals, your health history, your hormone levels, and the judgment of a licensed healthcare provider
About long-term planning: "What happens if I stop taking it ?" "How will we monitor my progress and adjust treatment?" "At what point would we consider switching to a different medication ?" Long-term questions impress doctors because they show you understand this is not a quick fix
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