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It does not appear to have toxic effects on the major organs, and it does not affect the endocrine (hormonal) system significantly
CD44, VEGF and CXCR4 can impair endothelial integrity to raise the transendothelial migration of tumor cells (110)
Systemic vs localized response mechanisms
I boiled it down to 46 rules in my book, Game Changers
These phosphorylated residues serve as docking sites for adapter proteins that initiate downstream signaling
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