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Increases in oxygen demand can worsen myocardial ischemia in some clinical settings (e.g
While GLP-1based therapies have been part of medical care for years, those medications have traditionally required injection
Presented for research literature review only Trappe SW et al
The SURMOUNT trials showed tirzepatide users lost approximately 20-22% of body weight at the highest doses, while STEP trials with semaglutide demonstrated approximately 15-17% reductions
Additionally, it can act as an appetite suppressant, though this side effect is not typically the primary reason people seek it out
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