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Circ.J 2010;74(10):2029-2038

Inhibition of CYP450 enzymatic activity protects hepatocytes from the toxic metabolites of APAP

Additionally, extended dexamethasone exposure has been shown to induce degenerative necrosis and inflammatory changes in hepatic tissues in experimental models (Ahmad, 2024)

It's possible that GLP-1 receptor agonists like Wegovy and Mounjaro may interfere with the sleep-wake cycle in some people, which may lead to insomnia or increased daytime sleepiness