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If you're already at maintenance dose and experiencing fatigue or cognitive symptoms despite adequate sleep and protein intake, begin NAC at 600mg twice daily and reassess subjective symptoms after 3 weeks
Womens Health (Lond)
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Chiang CH et al
However, long-term risks such as rare adverse effects, metabolic effects over years, effects on bone, gallbladder, and pancreas need phase-3 trials and post-marketing surveillance to ensure the medication is safe for long-term use
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