Retatrutide alone risks 20-30% muscle loss in total weight reduction, but combining with 1.6g protein per kg body weight daily and resistance training twice weekly preserves up to 70% more lean mass
Chanvillard, L., Tammaro, A
[28] [29] Before starting GLP-1 therapy, your healthcare provider will: Review your complete medical history, including thyroid disease status Ensure thyroid function is optimised Assess for any contraindications Discuss the benefits and risks specific to your situation With appropriate patient selection and monitoring, GLP-1 receptor agonists can be safely prescribed to individuals with Hashimoto's disease when the clinical benefits outweigh potential risks
(PubMed) Bone RC, Balk RA, Cerra FB, et al
Oral GLP-1 warnings You should not take Rybelsus if youve had an allergic reaction to Rybelsus, Ozempic, or Wegovy (the last two are injectable forms of semaglutide)