167 Lifestyle interventions and mitophagy Exercise interventions, particularly those combining multiple types, such as swimming and interval training, have demonstrated significant potential in enhancing mitophagy in animal models
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I have previously summarised the therapeutic pipeline for MASH (see links below) and in the past year we have seen the approval of Resmetirom, and now Semaglutide / ozempic is showing very impressive data in a Ph3 trial
Abbreviations GLP-1RA: Glucagon-like peptide-1 receptor agonist T2DM: Type 2 Diabetes Mellitus ADEs: Adverse Drug Events FAERS: FDA Adverse Event Reporting System ROR: Reporting Odds Ratio PRR: Proportional Reporting Ratio SOC: System Organ Class PT: Preferred Term CI: Confidence Interval References Wang L, Peng W, Zhao Z, Zhang M, Shi Z, Song Z, et al
ME, myalgic encephalomyelitis