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Mounjaro, which is manufactured by Eli Lilly, has seen patients in trials lose up to 20% of their weight after 72 weeks of treatment
Theres no direct evidence that tirzepatide itself causes missed periods, especially with gradual and moderate weight loss
The most compelling clinical studies use 12-week protocols
Native GLP-1 has a short half-life due to rapid degradation by dipeptidyl peptidase-4 (DPP-4) ( Figure 1 In recent years, growing evidence has highlighted a bidirectional interplay between GLP-1 RAs and the gut microbiome
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