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Weeks 1 through 4 at 2 mg
It slows gastric emptying, tempers the post-meal glucagon spike, and flips satiety switches in the hindbrain and hypothalamus
The promotion of renal-related inflammatory mechanisms occurs through TMAO activating NLRP3 inflammasomes and NF-B signal transduction, with NF-B playing a role in the DKD process by promoting vascular inflammation and oxidative stress, becoming a potential pathogenic mechanism in DKD (Huang et al., 2023) (Figure 10A)
For smaller vials or different target concentrations, adjust volume accordingly
