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Participants in these studies experienced average weight reductions that were notably greater than those observed in the placebo group, contributing to a healthy weight when combined with a reduced-calorie diet and healthy lifestyle changes

"NAION is a rare condition of the optic nerve that, although serious, has not really been shown to be increased by these studies," Decotiis, who was not involved in the research, told Fox News Digital

The same logic explains why these formulas also tend to include vitamin E, CoQ10, and L-carnitine rather than betting on one ingredient, so when you see a combined formula, you're usually looking at that principle in action, not just marketing