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Presented for research literature review only Mostafa T et al
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A sensitivity analysis excluding the ITCA trial reported a similar reduction in MACE as the pooled analysis (HR (95%CI): 0.86 (0.810.90)
Adherence to this dosing schedule matters more than jumping to higher doses rapidly
Necroptosis also induces macrophage IL-6 production, which upregulates CD47 on tumor cells, allowing immune evasion and driving liver metastasis and therapeutic resistance
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