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IV NAD therapies are not FDA-approved , have no standardized dosing, and may cause nausea, flushing, anxiety, or tachycardia

Glutathione injections are not a substitute for medical care, sun protection, diet, or exercise, and are not a treatment for any disease

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A meta-analysis of studies using NAC to increase athletic performance found that there were more side effects (none severe) at 20g/day.[ref] High doses of NAC are used in hospitals by IV for reversing acetaminophen toxicity