Significantly superior results were obtained in the group treated with the combination of acetyl L-carnitine and propionyl L-carnitine without sildenafil as compared to the group treated with sildenafil alone, in the tests recording nocturnal penile tumescence (Tables 5 and 10)
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The fact that L-carnitine supplementation didn`t add to the patients` seizure control was previously reported by Selter and collaborators who studied carnitine supplementation as one of dietary modifications to improve seizure control in patients on KDT and reported that this dietary modification wasn`t ideal for improving seizure control 24
The connection to MS is reinforced by the fact that ACTH, the parent hormone from which Semax derives, has established clinical utility in treating MS relapses, and enkephalins (whose degradation Semax inhibits) are implicated in multiple sclerosis pathophysiology