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An elevated or rising ratio during therapy indicates inflammation or tissue stress, a signal that cellular health is under strain
In this study of individuals with prehypertensionabout 130 over 80who took about the same amount, 1.6 g a day for 12 weeks, they got the same blood pressure benefit seen in the other trials, and, importantly, improvement in artery function compared to placebo
[8] One potential pathway appears to involve the activation of phospholipase C (PLC), which may lead to the release of inositol triphosphate (IP3) and diacylglycerol (DAG)
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