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S.SriretnakumarV.HahnM

Chinese Medical Journal, 125(15), 26772681

Its overactivation disrupts nicotinamide metabolism, reduces NAD+ levels, promotes hepatic lipid accumulation and lipotoxicity, and represents an important therapeutic target for hepatic metabolic disorders

Thymoquinone can increase the expression of mitochondrial ROS scavenging enzymes and antioxidant molecules, such as GPX, catalase, SOD and GSH, and restore renal mitochondrial viability via Nrf2 in various kidney diseases models (Hannan et al., 2021