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Complementing randomized trial evidence, extensive real-world observational data from large healthcare databases consistently demonstrate associations between GLP-1 receptor agonist utilization and decreased risks of MALOs involving cirrhosis, hepatic decompensation, HCC, and death from hepatic causes in patients with MASLD and type 2 diabetes

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The decision to initiate pharmacotherapy requires shared decision-making, discussing realistic expectations, potential adverse effects, cost considerations, and the likely need for indefinite treatment duration

What is Drug-Induced Liver Injury (DILI)

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