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Probenecid and cimetidine, which block active tubular secretion by targeting organic anion transporter (OAT)1 and 3, tend to have a greater impact in men, suggesting that male renal tubules have higher baseline transporter activity (Schwartz 2003

Functional genomics of OCTN2 variants informs protein-specific variant effect predictor for Carnitine Transporter Deficiency

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Work focuses on pathway mapping, assay development, and peptide SAR exclusively in controlled, non-clinical in-vitro environments