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FAQ How does BHRT work
42 LiuY.WanY.JiangY.ZhangL.ChengW
Usually, aldehyde-reactive alkoxyamines captured AP sites and blocked the activity of APE1 without selectivity towards different cells, causing side effects towards normal cells
107 In prostate cancer, anti-androgen therapies such as enzalutamide induce the histone reader ZMYND8, which cooperates with FOXM1 to activate neuroendocrine transcriptional programs (e.g., ASCL1), facilitating transdifferentiation into neuroendocrine prostate cancer (NEPC)
PMID 31621892
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