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J Inherit.Metab Dis 2007;30(1):5-22
Yet men remain underrepresented both in seeking weight loss treatment and in discussions about it
Reported effects Significant weight loss (1015% body weight reduction) Improved glycemic control Reduced appetite and food intake Potential cardiovascular benefits Convenient once-weekly dosing Reported side effects Nausea, vomiting, diarrhea, constipation, abdominal pain (most common, typically mild) Injection-site reactions (redness, swelling, irritation) Hypoglycemia (less common, mainly when combined with insulin/sulfonylureas) Rare serious risks: pancreatitis, gallbladder disease, acute kidney injury Storage Lyophilised (unmixed) Freeze at -20 C (-4 F) After reconstitution Refrigerate at 28 C (35.646.4 F) and use within 28 days Supplies Important notes Always use a new, sterile insulin syringe for each injection and dispose of it properly in a sharps container
For those prescribed semaglutide injections, the recommended dosage is 0.25 mg once weekly for 4 weeks as a non therapeutic dose
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