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The interventions varied in dosage and duration, ranging from 6 weeks to 104 weeks
Around 1520% of patients with IBD demonstrate hypermethylation when treated with thiopurines, resulting in preferential metabolism of MP to methylmercaptopurine (MeMP)[54]
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The characteristics of these three medications are summarized in the Supplementary Material, Tables S2 and S3
While no direct evidence links BPC-157 to cancer development, those with cancer history or known malignancy should avoid the peptide until more data exists
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