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10.1016/j.critrevonc.2022.103843 154 SuY.FangH.JiangF

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Adding semaglutide to retatrutide would duplicate GLP-1 receptor activation, which could increase side effects without proportionally increasing efficacy

Upon DNA damage, COP1 is inactivated through a process involving its dissociation from p53, ATM-mediated phosphorylation on COP1 S387, autoubiquitination and proteasome mediated degradation 30