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In the SUSTAIN 8 study, patients with T2DM exhibited a lean mass decrease of 2.3 kg alongside a total weight loss of 5.3 kg, resulting in 43.4% of weight loss attributable to lean mass, while the ratio of lean mass to total mass increased by 1.2% from the baseline [111]
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If the needle does not go deep enough, the medication may be deposited into the dermis, which is the thick layer of skin above the fat
doi: 10.1038/s41580-018-0092-0 15
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