Research has investigated its role in metabolic regulation, insulin sensitivity, and cellular aging through the AMPK pathway
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Check at baseline, 6-8 weeks after starting, after each 10-15 pounds of weight loss, every 3-4 months during active weight loss, and every 6 months after weight stabilization
Despite the visual appearance of a funnel plot, the small number of included studies significantly restricts the ability to rule out publication bias definitively, and the implementation of other statistical tests for asymmetry is underpowered with few studies and unreliable results