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The Frias 2023 Phase 2 in T2D showed cagrilintide+semaglutide produced a -2.2 percentage-point HbA1c reduction at 32 weeks versus -1.8 for semaglutide alone
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In one study 10 , elderly mice treated with 5-Amino-1MQ showed: ~40% stronger grip strength in sedentary conditions ~20% improvement with exercise ~60% boost when combined with exercise + therapy This suggests powerful benefits for maintaining strength and resilience with age
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