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The presence of a disulfide bridge, combined with the addition of tyrosine at the N-terminus, significantly enhances the peptides stability, making it orally active [8]

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Eligible participants are patients with T2DM who require adjustment or optimization of glucose-lowering therapy at baseline due to suboptimal glycaemic control or clinical indication for treatment modification

Whilst Rybelsus is the oral tablet formulation of semaglutide, the same active ingredient is available in injectable forms under different brand names

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