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Abstract Obesity in women of reproductive age has a number of adverse metabolic effects, including Type II Diabetes (T2D), dyslipidemia, and cardiovascular disease

No therapeutic, physiological or clinical outcome is represented

In a 26-week rat oral toxicity study, AOD-9604 produced dose-dependent changes in serum osteocalcin (a bone-turnover marker) at week 13, with the direction reversing by week 26

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Adjustments may account for changes in tolerance, weight loss response, or evolving health goals