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Proton magnetic resonance spectroscopy (1H-MRS) has detected reduced GABA concentrations in the frontal and motor cortices, cerebellum, anterior cingulate cortex, and sensorimotor regions of ASD patients, along with decreased ratios of GABA/glutamate, N-acetylaspartate/creatine, GABA/creatine, and glutamate/creatine
Screening for personal or family history of medullary thyroid carcinoma and MEN2 is essential, with patient counseling regarding symptoms such as neck mass, dysphagia, hoarseness, or dyspnea that warrant prompt evaluation
Some GI reactions are moderate to severe and induce the patient to quit therapy
Beyond potential side effects, relying on unproven patches may delay access to treatments that are known to be effective and can actually improve long-term health
/ A Certificate of Analysis (COA) is a document from a lab that proves the product was tested
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