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The expression of nNOS in cardiac tissue allows it, through the production of NO, to play essential roles in the modification of sympathetic and parasympathetic tone within the heart itself, in the regulation of heart rate, and in the delivery of essential nutrients through the coronary arteries as well as through the regulation of myocardial contractility
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When appetite suppression from semaglutide or tirzepatide makes eating difficult, prioritize protein above all other macronutrients
For instance, a prospective trial reported that semaglutide alleviated heart-failure-related symptoms and physical limitations in HFpEF patients (26)
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