Diabetes with evidence of complications: retinopathy, neuropathy and congestive heart failure as well as hypertension and obesity
Lai EC, Felice KJ, Festoff BW, Gawel MJ, Gelinas DF, Kratz R, Murphy MF, Natter HM, Norris FH, Rudnicki SA (1997) Effect of recombinant human insulin-like growth factor-I on progression of ALS: a placebo-controlled study
In some patients, insulin sensitivity may be reduced, as GH tends to raise blood glucose by antagonizing insulin
This has many practical applications, from accelerated injury healing and joint recovery to increased mobility and improved digestive function
Most gastrointestinal symptoms are mild to moderate in severity and tend to diminish over time as the body adjusts to the medication, particularly when dose escalation follows the recommended gradual titration schedule