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N Engl J Med, 2025
Comparing options: why oral products matter People often compare supplements to prescription injectables when thinking about weight or metabolic outcomes
L-Carnitine boosts cellular energy and helps transport fatty acids into the mitochondrial membrane for energy production
Research and clinical practice commonly use various thresholds, including regaining more than 25% of maximum weight lost or achieving a body mass index (BMI) above 35 kg/m with obesity-related comorbidities
Mitochondrial dysfunction in HD includes impaired electron transport chain activity, reduced mitochondrial biogenesis, and defective mitophagy, all of which contribute to increased oxidative stress and neuronal damage [165]
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