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Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention

This section presents current neuron-targeted therapeutic strategies, organized along a conceptual axis from extracellular modulation (e.g., receptor activation and trophic signaling) to intracellular mechanisms (e.g., signal transduction, transcriptional regulation and metabolic support)

Corresponding author: Karin Elgar (email [email protected])

GLP-1 drugs enhance this response, which can be particularly helpful among people with type 2 diabetes, who may have a reduced natural GLP-1 response

Studies have shown approximately 20% reduction in major adverse cardiovascular events