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Novel pro-GSH molecules as multi-functional antioxidants
Clinical trial data indicates tesofensine-induced weight loss consists predominantly of fat mass loss with notable preservation of lean body mass, a critical distinction from general caloric restriction which typically results in proportional loss of both fat and muscle tissue
doi:10.1097/AUD.0000000000000765
The investigators phenotypically analyzed a new 4-hydroxyl pyrazole scaffold for ferroptosis inhibitor 4-hydroxyl pyrazole derivatives (HW-3) (EC 50 = 120.1 3.5 nM) and synthesized a series of 4-hydroxyl pyrazole derivatives based on the backbone structure of HW-3
83 JosephsonA
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