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First characterised by Raun and colleagues at Novo Nordisk in 1998 (PMID: 9241518), Ipamorelin was designed to deliver potent GH stimulation with a selectivity profile that makes it tractable for isolated study of GH-axis effects without confounding stress-hormone activation
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Rotating injection sites helps minimize this
Unlike H1 and H2 histamine receptor antagonists, which showed inconsistent results across the different animal models, BPC-157 had a strong beneficial effect in both rats and mice
J.LeonS.et al (2007a)
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