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Intercurrent events such as smoking cessation, switching to or adding another weight-loss treatment, or treatment discontinuation, can be unbalanced between treatment arms and impact the endpoint of interest, and subsequent data analysis and interpretation
The clinical relevance of the treatment effect estimated using last observation on-treatment carried forward will be limited if trial participants tend to discontinue placebo earlier (or later) than participants in the active treatment group [4] since there is a risk of not comparing like with like in this type of analysis
Its fast, professional, and handled by trained healthcare staff
Suitable for in-vitro assay workflows, solvent screening, and stability/compatibility studies under standardized protocols
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