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If your primary concern is a vitamin deficiency, especially if youre on a plant-based diet, B12 could be the way to go

Yes, split dosing is a valid approach, particularly for doses at the higher end of the range (450-500mcg daily)

Medical News Today echoes this, emphasizing that the body tightly regulates its own pH

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These reactions are central to ATP generation, DNA repair, and cell signaling, so adequate B supports energy levels and normal cell function