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A pill form of the widely prescribed GLP-1 medication Ozempic is now available in the United States
The last 5 years have seen the emergence of efficacious peptide-based therapies for obesity treatment that target glucagon-like peptide-1 receptor (GLP-1R), either selectively or via co-activation with related receptors, such as the glucose-dependent insulinotropic polypeptide and/or glucagon receptors 1
It has been reported that long-term oral carnitine treatment for 6 months in a patient with carnitine deficiency resulted in increased muscle strength, significant reduction in heart size, relief from cardiomyopathy, and partial repletion of carnitine levels in plasma and muscle with complete repletion of liver functions (71)
A., Leong, P
Conclusion GLP-1 medications provide proven benefits for weight management and diabetes control, yet monthly costs of up to $1,000 without insurance create significant financial barriers for patients requiring long-term treatment
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