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However, when the reduced affinity was accounted for, exendin-phe1 and, to a lesser extent, lixi-phe1, were more efficiently coupled to cAMP production than the -asp3 versions (Figure 6C)
It targets two receptor pathways: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide)
[31] In response to the accumulation of the hazardous metabolic byproducts of aerobic respiration, biological systems evolved various strategies to counteract O 2 toxicity
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