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The color of our skin is primarily a reflection of the amount of melanin present in the body

Ethics declarations Ethics Approval and Consent to Participate Ethics approval was obtained from the Animal Ethics Committee of Joint Service Support Force 940 Hospital of PLA, and the experiment met the requirements of animal ethics

Patient Reported Outcomes Patients rated the degree of distress associated with their belly appearance on a 9-point rating scale that was then transformed to a score from 0 (extremely upsetting and distressing) to 100 (extremely encouraging)

Antigen-presenting cells recognized donor alloantigens and presented them on their surfaces, where they could be detected by T cells, contributing to allograft rejection, and resulting in interstitial fibrosis

Primarily, it boosts muscle strength and mass by binding to the IGF-1 receptor on muscle cells via the PI3K/Akt/mTOR and PI3K/Akt/GSK3 pathways