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For example, in pea plants susceptible to Plum pox virus (PPV), systemic PPV infection produced chlorotic and necrotic lesions, a pronounced oxidative stress indicated by increased protein oxidation, lipid peroxidation, elevated H 2 O 2 levels and electrolyte leakage in infected leaves (Daz-Vivancos et al., Rice black-streaked dwarf virus (RBSDV) displayed an induction of GST23 and the corresponding transcripts, concomitant with oxidative stress (Xu et al., 2013)

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The main challenge with oral supplementation is that glutathione is broken down in the digestive system before it can reach the brain

"New sensitization: the Medical Key to Treatment," Rocky Mountain Environmental Health Association, under "Hydrogen Peroxide has a Complex Role in Cell Health." Science Daily, 4 January 2008, ImmuneHealth.com, Benefits of selenium and its role as a glutathione cofactor