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Severe hepatic impairment lacks adequate safety data, making tirzepatide use in these patients rely on careful individual benefit risk assessment
A United States study found that it had no effect on ACTH, prolactin, follicle stimulating hormone, luteinizing hormone, Thyroid stimulating hormone, or cortisol secretion (1)
This is especially beneficial in medical settings, where the same vial may be used multiple times
10.1073/pnas.90.8.3569 97 GolubnitschajaO.DebaldM.YeghiazaryanK.KuhnW.PetaM.CostigliolaV.et al (2016)
Insert the needle into the vial through the rubber stopper
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