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Differences between two groups were determined by the unpaired Student's t-test, and differences between multiple groups were determined by one-way analysis of variance followed by Fisher's least significant difference test

EOT, end of treatment

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Nat Med 19(12):15841596 Kim DW, Glendining KA, Grattan DR, Jasoni CL (2016) Maternal obesity in the mouse compromises the blood-brain barrier in the arcuate nucleus of offspring

Ideal candidates for GLP-1 weight loss treatments are adults who struggle with obesity or have a BMI over 30, and those with weight-related medical conditions such as type 2 diabetes