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For instance, paeoniflorin directly binds to the glycolytic enzyme ENO1, inhibiting its activity and expression, thereby disrupting glucose metabolism and suppressing M1 polarization in microglia and macrophages, which alleviates central inflammation in experimental autoimmune encephalomyelitis (247)

Oral and IV glutathione supplements may be unsafe for women who are pregnant or breastfeeding, people who take prescription or over-the-counter medications, and those who have chronic conditions

Lancet HIV (2019) 3

In obese mice, chronic treatment with AOD-9604 increased fat oxidation and reduced weight gain, without the adverse effect on insulin sensitivity seen with intact growth hormone

This approach aligns with core concepts of precision nutrition (166)