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doi: 10.3389/fcell.2021.712124 72 GamulescuMAChenYHeSSpeeCJinMRyanSJet al

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GamageN.BarnettA.HempelN.DugglebyR

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Using Too Little Water Adding 0.5mL to a 5mg vial gives 10,000mcg/mL

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In mouse models of highfat dietinduced liver steatosis, it significantly inhibits hepatic NNMT activity, reduces NAM methylation, increases NAD+ and SAM levels, enhances mitochondrial fatty acid oxidation, reduces hepatic triglyceride and lipid accumulation, lowers lipotoxicity markers (e.g., malondialdehyde, transaminases), improves hepatocellular injury, and reverses steatosis

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